Publications
2023
My. V. T. Nguyen, Kate Dolph, Kris T. Delaney, Kevin Shen, Nicholas Sherck, Stephan Köhler, Rohini Gupta, Matthew B. Francis, M. Scott Shell, Glenn H. Fredrickson; Molecularly informed field theory for estimating critical micelle concentrations of intrinsically disordered protein surfactants. J. Chem. Phys. 28 December 2023
Bischoff AJ, Hamerlynck LM, Li AJ, Roberts TD, Ginsberg NS, Francis, MB. Protein-Based Model for Energy Transfer between Photosynthetic Light-Harvesting Complexes Is Constructed Using a Direct Protein-Protein Conjugation Strategy. J. Am. Chem. Soc.
Dai J, Wilhelm KW, Bischoff AJ, Pereira JH, Dedeo MT, García-Almedina DM, Adams PD, Groves JT, Francis MB. A membrane-associated light harvesting model is enabled by functionalized assemblies of gene-doubled TMV proteins. Small 2023
Cao W, Maza JC, Chernyak N, Flygare JA, Krska SW, Toste FD, Francis MB. Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions. Bioconjugate Chem. 2023
2022
Bischoff AJ, Conner CH, Williams ER, Francis MB. Characterizing Heterogeneous Mixtures of Assembled States of the Tobacco Mosaic Virus Using Charge Detection Mass Spectrometry. J. Am. Chem. Soc. 2022
Pistono PE, Huang P, Brauer DD, Francis MB. Fitness Landscape-Guided Engineering of Locally Supercharged Virus-like Particles with Enhanced Cell Uptake Properties. ACS Chem. Biol. 2022
Hamerlynck LM, Bischoff AJ, Rogers JR, Roberts TD, Dai J, Geissler PL, Francis MB, Ginsberg NS. Static Disorder has Dynamic Impact on Energy Transport in Biomimetic Light-Harvesting Complexes. J. Phys. Chem. B 2022
Miller ZM, Harper CC, Lee H, Bischoff AJ, Francis MB, Schaffer DV, Williams ER. Apodization Specific Fitting for Improved Resolution, Charge Measurement, and Data Analysis Speed in Charge Detection Mass Spectrometry. J. Am. Soc. Mass Spectrom. 2022
Harper CC, Miller ZM, Lee H, Bischoff AJ, Francis MB, Schaffer DV, Williams ER. Effects of Molecular Size on Resolution in Charge Detection Mass Spectrometry. Anal. Chem. 2022
Gleason JM, Klass SH, Huang P, Ozawa T, Santos RA, Fogarty MM, Raleigh DR, Berger MS, Francis MB. Intrinsically Disordered Protein Micelles as Vehicles for Convection-Enhanced Drug Delivery to Glioblastoma Multiforme. ACS Appl. Bio. Mater. 2022
Maza JC, García-Almedina DM, Boike LE, Hamlish NX, Nomura DK, Francis MB. Tyrosinase-Mediated Synthesis of Nanobody–Cell Conjugates. ACS Cent. Sci 2022
Hernandez ET, Koo B, Sofen LE, Amin R, Togashi RK, Lall AI, Gisch DJ, Kern BJ, Ricard MA, Francis MB. Proteins as Adsorbents for PFAS Removal from Water. Environ. Sci.: Water Res. Technol. 2022
Walker JA, Hamlish N, Tytla A, Brauer DD, Francis MB, Schepartz A. Redirecting RiPP Biosynthetic Enzymes to Proteins and Backbone-Modified Substrates. ACS Cent. Sci. 2022
Klass SH, Gleason JM, Omole AO, Onoa B, Bustamante CJ, Francis MB. Preparation of Bioderived and Biodegradable Surfactants Based on an Intrinsically Disordered Protein Sequence. Biomacromolecules 2022
2021
Mogilevsky CS, Lobba MJ, Brauer DD, Marmelstein AM, Maza JC, Gleason JM, Doudna JA, Francis MB. Synthesis of Multi-Protein Complexes through Charge-Directed Sequential Activation of Tyrosine Residues. J. Am. Chem. Soc. 2021
Stachl CN, Brauer DD, Mizuno H, Gleason JM, Rorrer JE, Francis MB, Baranger AM. Shaping the Future of Higher Education: Practical, Community-Driven Initiatives to Improve Academic Climate. ACS Cent. Sci. 2021
Stachl CN, Brauer DD, Mizuno H, Gleason JM, Francis MB, Baranger AM. Improving the Academic Climate of an R1 STEM Department: Quantified Positive Shifts in Perception. ACS Omega 2021
Ramsey AV, Bischoff AJ, Francis MB. Enzyme Activated Gold Nanoparticles for Versatile Site-Selective Bioconjugation. J. Am. Chem. Soc. 2021
Harper CC, Brauer DD, Francis MB, Williams ER. Direct observation of ion emission from charged aqueous nanodrops: effects on gaseous macromolecular charging. Chem. Sci. 2021
Klass SH, Sofen LE, Hallberg ZF, Fiala TA, Ramsey AV, Dolan NS, Francis MB, Furst AL. Covalent capture and electrochemical quantification of pathogenic E. coli. Chem. Comm. 2021
2020
Dai J, Knott GJ, Fu W, Lin TW, Furst AL, Britt RD, Francis MB. Protein-Embedded Metalloporphyrin Arrays Templated by Circularly Permuted Tobacco Mosaic Virus Coat Proteins. ACS Nano 2020
Bond KM, Aanei IL, Francis MB, Jarrold MF. Determination of Antibody Population Distributions for Virus-Antibody Conjugates by Charge Detection Mass Spectrometry. Anal. Chem. 2020
Lobba MJ, Fellman C, Marmelstein AM, Maza JC, Kissman EN, Robinson SA, Staahl BT, Urnes C, Lew RJ, Mogilevsky CS, Doudna JA, Francis MB. Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation. ACS Cent. Sci. 2020
Robinson SA, Hartman EC, Ikwuagwu BC, Francis MB, Tullman-Ercek D. Engineering a Virus-like Particle to Display Peptide Insertions Using an Apparent Fitness Landscape. Biomacromolecules 2020
Lin TY, Klass SH, Francis MB, Shaqfeh ESG. Extravasation of PEGylated Spherical Nanoparticles through a Circular Pore of Similar Size. Macromolecules 2020
Marmelstein AM, Lobba MJ, Mogilevsky CS, Maza JC, Brauer DD, Francis MB. Tyrosinase-Mediated Oxidative Coupling of Tyrosine Tags on Peptides and Proteins. J. Am. Chem. Soc. 2020
Maza JC, Ramsey AV, Mehare M, Krska S, Parish CA, Francis MB. Secondary Modification of Oxidatively-Modified Proline N-termini for the Construction of Complex Bioconjugates. Org. Biomol. Chem. 2020
2019
Bond KM, Aanei IL, Francis MB, Jarrold MF. Determination of Antibody Population Distributions for Virus-Antibody Conjugates by Charge Detection Mass Spectrometry. Anal. Chem. 2019
Koo B, Dolan NS, Wucherer K, Munch HK, Francis MB. Site-Selective Protein Immobilization on Polymeric Supports through N-Terminal Imidazolidinone Formation. Biomacromolecules 2019
Stachl CN, Hartman EC, Wemmer DE, Francis MB. Grassroots Efforts To Quantify and Improve the Academic Climate of an R1 STEM Department: Using Evidence-Based Discussions To Foster Community. J. Chem. Educ. 2019
García-Cerdán JG, Furst AL, McDonald KL, Schünemann D, Francis MB, Niyogi KK. A thylakoid membrane-bound and redox-active rubredoxin (RBD1) functions in de novo assembly and repair of photosystem II. Proc. Nat. Acad. Sci. 2019
Klass SH, Truxal AE, Fiala TA, Kelly J, Nguyen D, Finbloom JA, Wemmer DE, Pines A, Francis MB. Rotaxane probes for the detection of hydrogen peroxide by 129Xe hyperCEST NMR. Angew. Chem. Int. Ed. Engl. 2019
Klass SH, Smith MJ, Fiala T, Lee JP, Omole A, Han B-G, Downing KH, Francis MB. Self-Assembling Micelles Based on an Intrinsically Disordered Protein Domain. J. Am. Chem. Soc. 2019
Brauer DD, Hartman EC, Bader DLV, Merz ZN, Tullman-Ercek D, Francis MB. Systematic Engineering of a Protein Nanocage for High-yield, Site-specific Modification. J. Am. Chem. Soc. 2019
Maza JC, Bader DLV, Xiao L, Marmelstein AM, Brauer DD, ElSohly AM, Smith MJ, Krska SW, Parish CA, Francis MB. Enzymatic Modification of N-Terminal Proline Residues Using Phenol Derivatives. J. Am. Chem. Soc. 2019
Sangsuwan R, Tachachartvanich P, Francis MB. Cytosolic Delivery of Proteins Using Amphiphilic Polymers with 2-Pyridinecarboxaldehyde Groups for Site-Selective Attachment. J. Am. Chem. Soc. 2019
2018
Furst AL, Francis MB. Impedance-Based Detection of Bacteria. Chem. Rev. 2018
Jaffe J*, Wucherer K*, Sperry J, Zou Q, Chang Q, Massa MA, Battacharya K, Kumar S, Caparon M, Stead D, Wright P, Dirksen A, Francis MB. Effects of Conformational Changes in Peptide-CRM197 Conjugate Vaccines. Bioconjugate Chem. 2018
Lee J, Lee D, Kocherzhenko AA, Greenman L, Finley DT, Francis MB, Whaley KB. Molecular Mechanics Simulations and Improved Tight-Binding Hamiltonians for Artificial Light Harvesting Systems: Predicting Geometric Distributions, Disorder, and Spectroscopy of Chromophores in a Protein Environment. J. Phys. Chem. B. 2018
Finbloom JA,* Aanei IL,* Bernard JM,* Klass SH, Elledge SK, Han K, Ozawa T, Nicolaides TP, Berger MS, Francis MB. Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma. Nanomaterials. 2018
Hartman EC, Lobba MJ, Favor AH, Robinson SA, Francis MB, Tullman-Ercek D. Experimental evaluation of coevolution in a self-assembling particle. Biochemistry. 2018
Furst AL, Klass SH, Francis MB. DNA Hybridization to Control Cellular Interactions. Trends Biochem. Sci. 2018
Aanei IL, Huynh T, Seo Y, Francis MB. Vascular Cell Adhesion Molecule-Targeted MS2 Viral Capsids for the Detection of Early-Stage Atherosclerotic Plaques. Bioconjugate Chem. 2018
Finbloom JA, Francis MB. Supramolecular strategies for protein immobilization and modification. Curr. Opin. Chem. Biol. 2018
Furst AL, Smith MJ, Lee MC, Francis MB. DNA Hybridization To Interface Current-Producing Cells with Electrode Surfaces. ACS Central Science. 2018
ElSohly AM, Netirojjanakul C, Francis MB. Antibody Modification of p-Aminophenylalanine-Containing Proteins. Methods in Molecular Biology. 2018
Aanei IL, Glasgow JE, Capehart SL, Francis MB. Encapsulation of Negatively Charged Cargo in MS2 Viral Capsids. Methods in Molecular Biology. 2018
Aanei IL, Francis MB. Dual Surface Modification of Genome-Free MS2 Capsids for Delivery Applications. Methods in Molecular Biology. 2018
Furst AL, Smith MJ, Francis MB. New Techniques for the Generation and Analysis of Tailored Microbial Systems on Surfaces. Biochemistry. 2018
Smith MJ, Francis MB. Methods for Generating Microbial Cocultures that Grow in the Absence of Fixed Carbon or Nitrogen. Methods in Molecular Biology. 2018
Lei R, Lee JP, Francis MB, Kumar S. Structural Regulation of a Neurofilament-Inspired Intrinsically Disordered Protein Brush by Multisite Phosphorylation. Biochemistry. 2018
Delor M,* Dai J,* Roberts TD,* Rogers JR,* Hamed SM, Neaton JB, Geissler PL, Francis MB, Ginsberg NS. Exploiting Chromophore–Protein Interactions through Linker Engineering To Tune Photoinduced Dynamics in a Biomimetic Light-Harvesting Platform. J. Am. Chem. Soc. 2018
Hartman EC, Jakobson CM, Favor AH, Lobba MJ, Alvarez-Benedicto E, Francis MB, Tullman-Ercek D. Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle. Nat. Commun. 2018
2017
Furst AL, Smith MJ, Francis MB. Direct electrochemical bioconjugation on metal surfaces. J. Am. Chem. Soc. 2017
Finbloom JA, Han K, Slack CC, Furst AL, Francis MB. Cucurbit[6]uril-promoted click chemistry for protein modification. J. Am Chem. Soc. 2017
Rosen CB, Francis MB. Targeting the N terminus for site-selective protein modification. Nat. Chem. Biol. 2017
Knight AS,* Kulkarni RU,* Zhou EY, Franke JM, Miller EW, Francis MB. A modular platform to develop peptoid-based selective fluorescent metal sensors. Chem. Commun. 2017
ElSohly AM,* MacDonald JI,* Hentzen NB, Aanei IL, El Muslemany KM, Francis MB. Ortho-methoxyphenols as convenient oxidative bioconjugation reagents with application to site-selective heterobifunctional cross-linkers. J. Am. Chem. Soc. 2017
Smith MJ, Francis MB. Improving metabolite production in microbial co-cultures using a spatially constrained hydrogel. Biotechnology and Bioengineering. 2017
Palla KS,* Hurlburt TJ,* Buyanin AM, Somorjai GA, Francis MB. Site-selective oxidative coupling reactions for the attachment of enzymes to glass surfaces through DNA-directed immobilization. J. Am. Chem. Soc. 2017
Furst AL, Hoepker AC, Francis MB. Quantifying hormone disruptors with an engineered bacterial biosensor. ACS Central Science. 2017
Slack CC,* Finbloom JA,* Jeong K, Bruns CJ, Wemmer DE, Pines A, Francis MB. Rotaxane probes for protease detection by 129Xe hyperCEST NMR. Chem. Commun. 2017
2016
Bruns CJ, Liu H, Francis MB. Near-quantitative aqueous synthesis of rotaxanes via bioconjugation to oligopeptides and proteins. J. Am. Chem. Soc. 2016
Finbloom JA, Han K, Aanei IL, Hartman EC, Finley DT, Dedeo MT, Fishman M, Downing KH, Francis MB. Stable disk assemblies of a tobacco mosaic virus mutant as nanoscale scaffolds for applications in drug delivery. Bioconjugate Chem. 2016
Aanei IL, ElSohly AM, Netirojjanakul C, Regan M, Taylor Murphy S, O’Neil JP, Seo Y, Francis MB. Biodistribution of antibody-MS2 viral capsid conjugates in breast cancer models. Mol. Pharm. 2016
Jeong K, Netirojjanakul C, Munch HK, Sun J, Finbloom JA, Wemmer DE, Pines A, Francis MB. Targeted molecular imaging of cancer cells using MS2-based 129Xe NMR. Bioconjugate Chem. 2016
Gomes MD, Phuong D, Jeong K, Slack CC, Vassiliou CC, Finbloom JA, Francis MB, Wemmer DE, Pines A. 129Xe NMR relaxation-based macromolecular sensing. J. Am. Chem. Soc. 2016
Sangsuwan R, Obermeyer A, Tachachartvanich P, Palaniappan KK, Francis MB. Direct detection of nitrotyrosine-containing proteins using an aniline-based oxidative coupling strategy. Chem. Commun. 2016
Lee JP, Kassianidou E, MacDonald JI, Francis MB. N-terminal specific conjugation of extracellular matrix proteins to 2-pyridinecarboxaldehyde functionalized polyacrylamide hydrogels. Biomaterials. 2016
Smith MJ, Francis MB. A designed A. vinelandii-S. elongatus coculture for chemical photoproduction from air, water, phosphate, and trace metals. ACS Synth. Biol. 2016
Rosen CB, Kwant RL, MacDonald JI, Rao M, Francis MB. Capture and recycling of sortase A through site-specific labeling with lithocholic acid. Angew. Chem., Int. Ed. 2016.
Parker BF, Knight AS, Vukovic S, Arnold J, Francis MB. A peptoid-based combinatorial and computational approach to developing ligands for uranyl sequestration from seawater. Ind. Eng. Chem. Res. 2016
Finbloom JA, Slack CC, Bruns CJ, Jeong K, Wemmer DE, Pines A, Francis MB. Rotaxane-mediated suppression and activation of cucurbit[6]uril for molecular detection by 129Xe hyperCEST NMR. Chem. Commun. 2016.
2015
Carrico ZM, Strobel KL, Atreya ME, Clark DS, Francis MB. Simultaneous selection and counter-selection for the directed evolution of proteases in E. coli using a cytoplasmic anchoring strategy. Biotechnology and Bioengineering. 2015.
Jeong K, Slack CC, Vassiliou CC, Dao P, Gomes MD, Kennedy DJ, Truxal AE, Sperling LJ, Francis MB, Wemmer DE, Pines A. Investigation of DOTA-Metal Chelation Effects on 129Xe Chemical Shift. Chemphyschem. 2015.
ElSohly AM, Netirojjanakul C, Aanei IL, Jager A, Bendall S, Farkas ME, Nolan GP, Francis MB. Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-based Cell Targeting. Bioconjugate Chem. 2015
Knight AS, Zhou EY, Francis MB. Development of peptoid-based ligands for the removal of cadmium from biological media. Chemical Science 2015.
ElSohly AM and Francis MB. Development of Oxidative Coupling Strategies for Site-Selective Protein Modification. Accounts of Chemical Research 2015.
Noriega R, Finley DT, Haberstroh J, Geissler PL, Francis MB, Ginsberg NS. Manipulating Excited-State Dynamics of Individual Light-Harvesting Chromophores through Restricted Motions in a Hydrated Nanoscale Protein Cavity. J Phys Chem B 2015.
Glasgow JE, Asensio MA, Jakobson CM, Francis MB, Tullman-Ercek D. The Influence of Electrostatics on Small Molecule Flux through a Protein Nanoreactor. ACS Synth Biol. 2015.
Knight AS, Zhou EY, Francis MB, Zuckermann RN. Sequence Programmable Peptoid Polymers for Diverse Materials Applications. Advanced Materials 2015.
MacDonald, JI, Munch HK, Moore T, Francis MB. One-step site-specific modification of native proteins with 2-pyridinecarboxaldehydes. Nat. Chem. Biol. 2015.
Kwant RL, Jaffe J, Palmere PJ, Francis MB. Controlled levels of protein modification through a chromatography-mediated bioconjugation. Chemical Science 2015.
2014
Bernard JM, Francis MB. Chemical strategies for the covalent modification of filamentous phage. Front Microbiol. 2014.
Palla KS, Witus LS, Mackenzie KJ, Netirojjanakul C, Francis MB. Optimization and expansion of a site selective N-methylpyridinium-4-carboxaldehyde mediated transamination for bacterially expressed proteins. JACS 2014. Link.
Capehart SL, ElSohly AM, Obermeyer AC, Francis MB. Bioconjugation of Gold Nanoparticles through the Oxidative Coupling of ortho-Aminophenols and Anilines. Bioconjug Chem. 2014. Link.
El Muslemany KM, Twite AA, ElSohly AM, Obermeyer AC, Mathies RA, Francis MB. Photoactivated Bioconjugation Between ortho-Azidophenols and Anilines: A Facile Approach to Biomolecular Photopatterning. JACS 2014. Link.
Wang D, Capehart SL, Pal S, Liu M, Zhang L, Schuck PJ, Liu Y, Yan H, Francis MB, De Yoreo JJ. Hierarchical Assembly of Plasmonic Nanostructures Using Virus Capsid Scaffolds on DNA Origami Templates. ACS Nano 2014. Link.
Obermeyer AC, Capehart SL, Jarman JB, Francis MB. Multivalent viral capsids with internal cargo for fibrin imaging. PLOS One. 2014. Link.
Obermeyer AC, Jarman JB, Francis MB. N-Terminal Modification of Proteins with o-Aminophenols. JACS. 2014. Link.
MacKenzie, KJ and Francis, MB. Effects of NIPAm polymer additives on the enzymatic hydrolysis of avicel and pretreated miscanthus. Biotechnology and Bioengineering. 2014. Link
2013
Garimella PD, Meldrum T, Witus LS, Smith M, Bajaj VS, Wemmer DE, Francis MB, Pines A. Hyperpolarized xenon-based molecular sensors for label-free detection of analytes. J. Am. Chem. Soc. 2013. Link
Obermeyer AC, Jarman JB, Netirojjanakul C, El Muslemany K, Francis MB. Mild Bioconjugation Through the Oxidative Coupling of ortho-Aminophenols and Anilines with Ferricyanide. Angew Chem Int Ed Engl. 2013. Link
Knight AS, Zhou EY, Pelton JG, Francis MB. Selective Chromium(VI) Ligands Identified Using Combinatorial Peptoid Libraries. J. Am. Chem. Soc. 2013. Link
Witus LS, Netirojjanakul C, Palla KS, Muehl EM, Weng CH, Iavarone AT, Francis MB. Site-Specific Protein Transamination Using N-Methylpyridinium-4-carboxaldehyde. J. Am. Chem. Soc. 2013. 135(45):17223-9. Link
Sack JT, Stephanopoulos N, Austin DC, Francis MB, Trimmer JS. Antibody-guided photoablation of voltage-gated potassium currents. J. Gen. Physiol. 2013. 142(3): 315-24. Link
Hsiao SC, Liu H, Holstlaw TA, Liu C, Francis CY, Francis MB. Real time assays for quantifying cytotoxicity with single cell resolution. PLoS One 2013; e66739. Link
Palaniappan KK, Ramirez RM, Bajaj VS, Wemmer DE, Pines A, Francis MB. Molecular Imaging of Cancer Cells Using a Bacteriophage-Based 129Xe NMR Biosensor. Angew. Chem., Int. Ed. 2013; 52(18): 4849-53. Link
Coyle MP, Xu Q, Chiang S, Francis MB, Groves JT. DNA-Mediated Assembly of Protein Heterodimers on Membrane Surfaces. J. Am. Chem. Soc. 2013; 135 (13): 5012–6 Link
Capehart SL, Coyle MP, Glasgow JE, Francis MB. Controlled Integration of Gold Nanoparticles and Organic Fluorophores Using Synthetically Modified MS2 Viral Capsids. J. Am. Chem. Soc. 2013; 135 (8): 3011-6. Link
Mackenzie KJ, Francis MB. Recyclable Thermoresponsive Polymer-Cellulase Bioconjugates for Biomass Depolymerization. J Am Chem Soc. 2013; 135 (1): 293-300. Link
Farkas ME, Aanei IL, Behrens CR, Tong GJ, Murphy ST, O’Neil JP, Francis MB. PET Imaging and Biodistribution of Chemically Modified Bacteriophage MS2. Mol Pharm. 2013; 10 (1): 69-76 Link
Netirojjanakul, C, Witus LS, Behrens, CR, Weng, CH, Iavarone AT, Francis MB. Synthetically modified Fc domains as building blocks for immunotherapy applications. Chem. Sci. 2013; 4 (1): 266-272. Link
2012
Glasgow JE, Capehart SL, Francis MB, Tullman-Ercek D. Osmolyte-Mediated Encapsulation of Proteins inside MS2 Viral Capsid. ACS Nano. 2012; 6(10):8658-64. Link
Carrico ZM, Farkas ME, Zhou Y, Hsiao SC, Marks JD, Chokhawala H, Clark DS, Francis MB. N-Terminal Labeling of Filamentous Phage To Create Cancer Marker Imaging Agents. ACS Nano. 2012; 6(8):6675-80. Link
Stevens TK, Palaniappan KK, Ramirez RM, Francis MB, Wemmer DE, Pines A. HyperCEST detection of a (129) Xe-based contrast agent composed of cryptophane-A molecular cages on a bacteriophage scaffold. Magn Reson Med. 2012. Link
Onoe H, Hsiao SC, Douglas ES, Gartner ZJ, Bertozzi CR, Francis MB, Mathies RA. Cellular microfabrication: observing intercellular interactions using lithographically-defined DNA capture sequences. Langmuir. 2012; 28(21): 8120-6. Link
Twite AA, Hsiao SC, Onoe H, Mathies RA, Francis MB. Direct Attachment of Microbial Organisms to Material Surfaces Through Sequence-Specific DNA Hybridization. Adv Mater. 2012; 24(18): 2380-5. Link
2011
Stephanopoulos N, Francis MB. Choosing an effective protein bioconjugation strategy. Nat Chem Biol. 2011; 7(12):876-84. Link
Dedeo MT, Finley DT, Francis MB. Viral capsids as self-assembling templates for new materials. Prog Mol Biol Transl Sci. 2011; 103:353-92. Link
Seim KL, Obermeyer AC, Francis MB. Oxidative Modification of Native Protein Residues Using Cerium(IV) Ammonium Nitrate. J Am Chem Soc. 2011; 7(12):876-84. Link
Behrens CR, Hooker JM, Obermeyer AC, Romanini DW, Katz EM, Francis MB. Rapid Chemoselective Bioconjugation Through the Oxidative Coupling of Anilines and Aminophenols. J Am Chem Soc. 2011;133(41):16398-401Link
Witus LS, Francis MB. Using Synthetically Modified Proteins to Make New Materials. Acc Chem Res. 2011; 44(9):774-83. Link
Garimella PD, Datta A, Romanini DW, Raymond KN, Francis MB. Multivalent, high-relaxivity MRI contrast agents using rigid cysteine-reactive gadolinium complexes. J Am Chem Soc.2011;133(37):14704-9. Link
2010
Francis MB, Carrico I. New frontiers in protein bioconjugation. Curr Opin Chem Biol. 2010;14(6):771-3. Link
Witus LS, Moore T, Thuronyi BW, Esser-Kahn AP, Scheck RA, Iavarone AT, Francis MB. Identification of Highly Reactive Sequences For PLP-Mediated Bioconjugation Using a Combinatorial Peptide Library. J Am Chem Soc. 2010;132(47):16812-7. Link
Holder PG, Finley DT, Stephanopoulos N, Walton R, Clark DS, Francis MB. Dramatic thermal stability of virus-polymer conjugates in hydrophobic solvents. Langmuir. 2010;26(22):17383-8. Link
Stephanopoulos N, Tong GJ, Hsiao SC, Francis MB. Dual-surface modified virus capsids for targeted delivery of photodynamic agents to cancer cells. ACS Nano. 2010 Oct 26;4(10):6014-20. Link
Esser-Kahn AP, Trang V, Francis MB. Incorporation of antifreeze proteins into polymer coatings using site-selective bioconjugation. J Am Chem Soc. 2010 Sep 29;132(38):13264-9. Link
Witus LS and Francis MB. Site-Specific Protein Bioconjugation via a Pyridoxal 5′-Phosphate-Mediated N-Terminal Transamination Reaction. Curr Protoc in Chem Biol. 2010;125–134.
Stephanopoulos N, Liu M, Tong GJ, Li Z, Liu Y, Yan H, Francis MB. Immobilization and one-dimensional arrangement of virus capsids with nanoscale precision using DNA origami.Nano Lett. 2010;10(7):2714-20. Link
Crochet AP, Kabir MM, Francis MB, Paavola CD. Site-selective dual modification of periplasmic binding proteins for sensing applications. Biosens Bioelectron. 2010;26(1):55-61. Link
Miller RA, Stephanopoulos N, McFarland JM, Rosko AS, Geissler PL, Francis MB. Impact of assembly state on the defect tolerance of TMV-based light harvesting arrays. J Am Chem Soc. 2010;132(17):6068-74. Link
Meldrum T, Seim KL, Bajaj VS, Palaniappan KK, Wu W, Francis MB, Wemmer DE, Pines A. A xenon-based molecular sensor assembled on an MS2 viral capsid scaffold. J Am Chem Soc: 2010; 132(17):5936-7.Link
Dedeo MT, Duderstadt KE, Berger JM, Francis MB. Nanoscale Protein Assemblies from a Circular Permutant of the Tobacco Mosaic Virus. Nano Lett. 2010;10(1):181-186. Link
2009
Antos JM, McFarland JM, Iavarone AT, Francis MB. Chemoselective Tryptophan Labeling with Rhodium Carbenoids at Mild pH. J. Am. Chem. Soc. 2009;131(17):6301-6308. Link
Douglas ES, Hsiao SC, Onoe H, et al. DNA-barcode directed capture and electrochemical metabolic analysis of single mammalian cells on a microelectrode array. Lab Chip. 2009;9(14):2010-2015. Link
Hsiao SC, Shum BJ, Onoe H, et al. Direct Cell Surface Modification with DNA for the Capture of Primary Cells and the Investigation of Myotube Formation on Defined Patterns.Langmuir. 2009;25(12):6985-6991. Link
Stephanopoulos N, Carrico ZM, Francis MB. Nanoscale Integration of Sensitizing Chromophores and Porphyrins with Bacteriophage MS2. Angew. Chem., Int. Ed.2009;48(50):9498-9502, S9498/1-S9498/14. Link
Tilley SD, Joshi NS, Francis MB. Proteins: chemistry and chemical reactivity. In: Wiley Encycl. Chem. Biol.Vol 4. John Wiley & Sons, Inc.; 2009:158-174.
Tong GJ, Hsiao SC, Carrico ZM, Francis MB. Viral Capsid DNA Aptamer Conjugates as Multivalent Cell-Targeting Vehicles. J. Am. Chem. Soc. 2009;131(31):11174-11178. Link
Wu W, Hsiao SC, Carrico ZM, Francis MB. Genome-Free Viral Capsids as Multivalent Carriers for Taxol Delivery. Angew. Chem., Int. Ed. 2009;48(50):9493-9497, S9493/1-S9493/12. Link
2008
Carrico ZM, Romanini DW, Mehl RA, Francis MB. Oxidative coupling of peptides to a virus capsid containing unnatural amino acids. Chem. Commun. 2008;(10):1205-1207. Link
Chung S, Presley AD, Elhadj S, et al. Scanning probe-based fabrication of 3D nanostructures via affinity templates, functional RNA, and meniscus-mediated surface remodeling. Scanning. 2008;30(2):159-171. Link
Datta A, Hooker JM, Botta M, et al. High Relaxivity Gadolinium Hydroxypyridonate-Viral Capsid Conjugates: Nanosized MRI Contrast Agents. J. Am. Chem. Soc.2008;130(8):2546-2552. Link
Esser-Kahn AP, Francis MB. Protein-cross-linked polymeric materials through site-selective bio-conjugation. Angew. Chem., Int. Ed. 2008;47(20):3751-3754. Link
Esser-Kahn AP, Iavarone AT, Francis MB. Metallothionein-Cross-Linked Hydrogels for the Selective Removal of Heavy Metals from Water. J. Am. Chem. Soc. 2008;130(47):15820-15822. Link
Hooker JM, O’Neil JP, Romanini DW, Taylor SE, Francis MB. Genome-free viral capsids as carriers for positron emission tomography radiolabels. Mol Imaging Biol. 2008;10(4):182-91. Link
Hsiao SC, Crow AK, Lam WA, et al. DNA-coated AFM cantilevers for the investigation of cell adhesion and the patterning of live cells. Angew. Chem., Int. Ed. 2008;47(44):8473-8477. Link
Ma Y, Miller RA, Fleming GR, Francis MB. Energy Transfer Dynamics in Light-Harvesting Assemblies Templated by the Tobacco Mosaic Virus Coat Protein. J. Phys. Chem. B. 2008;112(22):6887-6892. Link
McFarland JM, Joshi NS, Francis MB. Characterization of a Three-Component Coupling Reaction on Proteins by Isotopic Labeling and Nuclear Magnetic Resonance Spectroscopy.J. Am. Chem. Soc. 2008;130(24):7639-7644. Link
Romanini DW, Francis MB. Attachment of Peptide Building Blocks to Proteins Through Tyrosine Bioconjugation. Bioconjugate Chem. 2008;19(1):153-157. Link
Scheck RA, Dedeo MT, Iavarone AT, Francis MB. Optimization of a Biomimetic Transamination Reaction. J. Am. Chem. Soc. 2008;130(35):11762-11770. Link
Toriello NM, Douglas ES, Thaitrong N, et al. Integrated microfluidic bioprocessor for single-cell gene expression analysis. Proc Natl Acad Sci U S A. 2008;105(51):20173-8. Link
2007
Douglas ES, Chandra RA, Bertozzi CR, Mathies RA, Francis MB. Self-assembled cellular microarrays patterned using DNA barcodes. Lab Chip. 2007;7(11):1442-1448. Link
Francis MB. New methods for protein bioconjugation. In: Chem. Biol.Vol 2. Wiley-VCH Verlag GmbH & Co. KGaA; 2007:593-634. Link
Francis MB, Doudna-Cate JH. Chemical Biology at Berkeley. ACS Chem. Biol.2007;2(11):702-705. Link
Holder PG, Francis MB. Integration of a self-assembling protein scaffold with water-soluble single-walled carbon nanotubes. Angew. Chem., Int. Ed. 2007;46(23):4370-4373. Link
Hooker JM, Datta A, Botta M, Raymond KN, Francis MB. Magnetic Resonance Contrast Agents from Viral Capsid Shells: A Comparison of Exterior and Interior Cargo Strategies.Nano Lett. 2007;7(8):2207-2210. Link
Johnson HR, Hooker JM, Francis MB, Clark DS. Solubilization and stabilization of bacteriophage MS2 in organic solvents. Biotechnol. Bioeng. 2007;97(2):224-234. Link
Kovacs EW, Hooker JM, Romanini DW, et al. Dual-Surface-Modified Bacteriophage MS2 as an Ideal Scaffold for a Viral Capsid-Based Drug Delivery System. Bioconjugate Chem.2007;18(4):1140-1147. Link
Miller RA, Presley AD, Francis MB. Self-Assembling Light-Harvesting Systems from Synthetically Modified Tobacco Mosaic Virus Coat Proteins. J. Am. Chem. Soc.2007;129(11):3104-3109. Link
Scheck RA, Francis MB. Regioselective labeling of antibodies through N-terminal transamination. ACS Chem. Biol. 2007;2(4):247-251. Link
2006
Antos JM, Francis MB. Transition metal catalyzed methods for site-selective protein modification. Curr. Opin. Chem. Biol. 2006;10(3):253-262.
Chandra RA, Douglas ES, Mathies RA, Bertozzi CR, Francis MB. Programmable cell adhesion encoded by DNA hybridization. Angew. Chem., Int. Ed. 2006;45(6):896-901.
Gilmore JM, Scheck RA, Esser-Kahn AP, Joshi NS, Francis MB. N-terminal protein modification through a biomimetic transamination reaction. Angew. Chem., Int. Ed.2006;45(32):5307-5311.
Hooker JM, Esser-Kahn AP, Francis MB. Modification of Aniline Containing Proteins Using an Oxidative Coupling Strategy. J. Am. Chem. Soc. 2006;128(49):15558-15559.
Nguyen T, Joshi NS, Francis MB. An Affinity-Based Method for the Purification of Fluorescently-Labeled Biomolecules. Bioconjugate Chem. 2006;17(4):869-872.
Tilley SD, Francis MB. Tyrosine-Selective Protein Alkylation Using π-Allylpalladium Complexes. J. Am. Chem. Soc. 2006;128(4):1080-1081.
2005
McFarland JM, Francis MB. Reductive Alkylation of Proteins Using Iridium Catalyzed Transfer Hydrogenation. J. Am. Chem. Soc. 2005;127(39):13490-13491.
Schlick TL, Ding Z, Kovacs EW, Francis MB. Dual-surface modification of the Tobacco mosaic virus. J. Am. Chem. Soc. 2005;127(11):3718-3723.
2004
Antos JM, Francis MB. Selective tryptophan modification with rhodium carbenoids in aqueous solution. J. Am. Chem. Soc. 2004;126(33):10256-10257.
Hooker JM, Kovacs EW, Francis MB. Interior surface modification of bacteriophage MS2.J. Am. Chem. Soc. 2004;126(12):3718-3719.
Joshi NS, Whitaker LR, Francis MB. A Three-Component Mannich-Type Reaction for Selective Tyrosine Bioconjugation. J. Am. Chem. Soc. 2004;126(49):15942-15943.
2003
Nguyen T, Francis MB. Practical synthetic route to functionalized rhodamine dyes. Org. Lett. 2003;5(18):3245-3248.